We weave strategic media buys,
smart creative and cutting-edge
technology around brands.

Data informs us. Content defines us. Media unites us. Technology binds us. Creativity liberates us.

Media (context), communications (creative/content) and technology (connections) represent the core capabilities of Greater Than One. Our proprietary convergence model strategically employs these capabilities to deliver behavior-changing customer experiences that drive better outcomes. And better outcomes mean better business results.

No holding company,
no holds barred.

Greater Than One is a part of GTO Group. We’re built to combine the best of all worlds from agency, media, and enterprise. That gets you more expertise, more well-rounded solutions, and more of your needs met, efficiently.

And we’re proud to share that we’re the only independent agency that is certified as both a WBE (Women Business Enterprise) and LGBTQ+ organization.


OUS on-demand

Our leaders

GTO Founder/CEO - Elizabeth Izard Appelles

President and CEO

Izard Apelles

Elizabeth leads all of Greater Than One. She is responsible for ensuring we deliver to our clients, anticipate opportunities, and capitalize on white space. Elizabeth also leads Greater Good, our 501(c)(3) dedicated to giving back, and Honeycomb Health, a technology platform geared towards families with rare genetic disease.

Chief Client Officer


Bindhu is a strategic account leader with 18+ years of demonstrated leadership in the pharmaceutical arena. She has helped to shape global strategy, launch brands and lead U.S. and global accounts in a variety of therapeutic areas. At Greater Than One, Bindhu is pivotal in driving growth for clients and building energized and successful account teams that deliver results. 

Chief Marketing Officer - Amanda Powers-Han

Chief Media and Marketing Officer


Amanda is an established healthcare marketing and communications leader with 25 years of experience.  As Chief Media and Marketing Officer, Amanda is responsible for overseeing the media practice, leading agency marketing efforts, and collaborating across clients to help create customer experiences that power their brands and business.

Chief Digital Officer


As Chief Digital Officer, Brian collaborates with Client Services, Media and Creative teams at Greater Than One to reimagine all aspects of their clients digital experiences and accelerate change across their digital ecosystem. He is passionate about blending design, data, and cross-functional teams to create experiences that people love. Brian has over 25 years of experience working at the intersection of technology, data, and people to help global organizations leverage new business models that drive growth.

Chief Financial Officer


Preston is a strategic finance leader with 16+ years of experience at media and digital agencies. He has extensive experience revamping agency financial operations and commercializing new product offerings to deliver client value. He oversees the finance function at Greater Than One and partners with executive leadership to drive optimal financial performance and commercial excellence at the agency.

Chief Operations Officer


Jason has devoted over 20 years of his career to pharmaceutical marketing and advertising, demonstrating a track record of launching successful brands both in the US and globally. He envisions Project Management and Operations as strategic partners and has developed unique processes that optimize efficiency, ensure control, and enable seamless execution. Recognizing that there is no “one-size-fits-all” approach to process, Jason collaborates closely with his team and clients to identify the best practices that will ensure the tactical delivery of client strategies and aligned initiatives.

Executive Vice President (EVP),
Strategy – Brand and Medical

Mary Rose
Burnham, PhD

With over 15+ years of experience in healthcare communications and marketing, Mary Rose is an experienced strategic leader who brings a fully integrated approach to developing and nurturing brands at Greater Than One. As Head of Strategy, overseeing both Brand and Medical Strategy, Mary Rose helps customers build brands that are rooted in science, guided by behavioral insights, and developed with the customer always at the center of every experience.

Executive Vice President (EVP),
Executive Creative Director


Mindy is a creative leader whose work has changed peoples’ minds, behaviors, and outcomes for the better. For 20 years, she has dedicated herself to elevating health and wellness communications beyond the status quo. As Creative lead at Greater Than One, her mission is to inspire the next generation of technology-enabled healthcare experiences that change people’s lives, one award winning creative idea at a time.

Executive Creative Director


Pilar has 15+ years of experience in omni-channel marketing and advertising in the health and wellness space. She is a builder of brands and customer experiences that fulfill user needs and drive business results. She is passionate about pushing ideas further through powerful storytelling, beautiful design and the latest technologies. She creates visionary experiences that transform brands.

SVP, People & Development Director


Jen is a collaborative and supportive human resources leader with over 20 years of experience. Recognizing that people are at the center of everything we do, a strong focus on talent helps ensure successful operations and an engaged community. Her ability to provide insights related to skill gaps, job satisfaction, and employment trends contribute towards making Greater Than One’s People-First culture even stronger.


These are the clients who have allowed us to bring our ideas to the table and collaborate to create something that’s simply better.

Vitas Logo

So what does better look like?

We could tell you, but we’ll let our work speak for itself.